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Healthcare Professionals: Research

Research – Clinical Trials

The severe eczema and psoriasis teams at St John’s Institute are actively involved in clinical research in dermatology. This research provides a better understanding of what causes skin, conditions, provides the newest in skin treatment and personalises available therapies to individual patients to maximise their effect and minimise side effects. The research team run trials with the latest therapies emerging in the fields of eczema and psoriasis.


If you are interested in learning more about our research in eczema or psoriasis or taking part in clinical trials in these areas please click on this link to the Guy’s & St Thomas NHS Foundation Trust website or you can email the team at

Paediatric Dermatology – Unit for Population-Based Dermatology Research

The Unit for Population-Based Dermatology Research is based at the St Thomas’ Hospital Campus and headed by Carsten Flohr, Professor and Consultant Dermatologist, and conducts translational and clinical research into the prevention, epidemiology and treatment of skin diseases, with a particular focus on paediatric atopic eczema. This is done through collaboration on large cohort and intervention studies, such as the Enquiring About Tolerance (EAT) study, the PROmotion of Breastfeeding Intervention Trial (PROBIT), and the International Study of Asthma and Allergies in Childhood (ISAAC). The Unit also leads a national trial comparing the efficacy, safety and cost-effectiveness of cyclosporine with methotrexate in severe paediatric eczema (TREAT trial) as well as an eczema prevention trial with water softeners (SOFTER), and the UK-Irish Atopic eczema Systemic TherApies Register (A*STAR).

A national cohort study of adult and paediatric patients on conventional and novel biologic treatments for severe atopic eczema is currently in set up.

Other useful links for healthcare professionals

Learn more about our Training Programmes

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